Immortalization of human and animal cells

  • Immortalization of primary human B lymphocytes
  • Immortalization of primary mammalian fibroblasts
  • Immortalization of avian embryonic fibroblasts

Transgenesis of human and animal cells

  • Gene knockout in human and animal cell lines
  • Introduction of point mutations (single nucleotide substitutions)
  • Integration of sequences into the genome of human and animal cells using the Sleeping Beauty system
  • Integration of sequences into the genome of human and animal cells using the PiggyBac system
  • Integration of sequences into the genome of human and animal cells into Safe Harbor loci (Rosa, Hipp11)
  • Integration of sequences into any loci via homologous recombination
  • Generation of inducible systems based on loxP sites and Cre recombinase
  • Generation of doxycycline-inducible systems
  • Generation of reporter systems in human and animal cells using fluorescent proteins
  • Creation of producer cell lines for the production of target proteins

Our company offers a wide range of services for developing research tools and models for biomedical studies. We take on part of your routine work involved in generating various types of cellular models and any vectors. The list above includes typical tasks; however, our specialists are ready to carry out custom projects tailored to the goals of your specific study. Since each task is unique, pricing is calculated individually. Contact us and we will be happy to consult you on any questions.

Immortalization of human and animal cells

  • Immortalization of primary human B lymphocytes
  • Immortalization of primary mammalian fibroblasts
  • Immortalization of avian embryonic fibroblasts

Transgenesis of human and animal cells

  • Gene knockout in human and animal cell lines
  • Introduction of point mutations (single nucleotide substitutions)
  • Integration of sequences into the genome of human and animal cells using the Sleeping Beauty system
  • Integration of sequences into the genome of human and animal cells using the PiggyBac system
  • Integration of sequences into the genome of human and animal cells into Safe Harbor loci (Rosa, Hipp11)
  • Integration of sequences into any loci via homologous recombination
  • Generation of inducible systems based on loxP sites and Cre recombinase
  • Generation of doxycycline-inducible systems
  • Generation of reporter systems in human and animal cells using fluorescent proteins
  • Creation of producer cell lines for the production of target proteins

Our company offers a wide range of services for developing research tools and models for biomedical studies. We take on part of your routine work involved in generating various types of cellular models and any vectors. The list above includes typical tasks; however, our specialists are ready to carry out custom projects tailored to the goals of your specific study. Since each task is unique, pricing is calculated individually. Contact us and we will be happy to consult you on any questions.